Christina Chandras

Scientific professional with a PhD and a background in biomedical research, biochemistry, and reproductive endocrinology. Experienced in writing, editing, and managing scientific documents, with a careful approach to synthesizing complex information and ensuring clarity and accuracy. Skilled in scientific data management and familiar with handling and curating research databases. Proficient in translating and transcribing biomedical texts between Greek and English, with solid knowledge of relevant scientific terminology. Known for being reliable, adaptable, and detail-oriented in collaborative environments.

• Mouse Nomenclature Training, 1-week training at the Jackson Laboratory, Bar Harbor, Maine, USA

Scientific Papers

(1) Fowkes RC, Chandras C, Chin EC, Okolo S, Abayasekara DRE & Michael AE (2001) Relationship between the production of prostaglandins and progesterone by luteinizing human granulosa cells. Journal of Endocrinology 171(3): 455-462

(2) Thurston LM, Norgate DP, Jonas KC, Chandras C, Kloosterboer HJ, Cooke BA, Michael AE. (2002) Ovarian modulators of 11beta-hydroxysteroid dehydrogenase (11betaHSD) activity in follicular fluid from gonadotrophin-stimulated assisted conception cycles. Reproduction 124(6): 801-12.

(3) Karalis KP, Venihaki M, Zhao J, van Vlerken LE, Chandras C.(2004) NF-kappaB participates in the corticotropin-releasing, hormone-induced regulation of the pituitary proopiomelanocortin gene. J Biol Chem. 279(12): 10837-40.

(4) Chandras C, Ragoobir J, Bruckdorfer KR, Graham A, Abayasekara DER & Michael AE (2004) Role for prostaglandins in the steroidogenic action of HDL in human granulosa-lutein cells. Mol Cell Endocrinol. 222(1-2): 1-8.

(5) Benou C, Wang Y, Imitola J, van Vlerken L, Chandras C, Karalis KP, Khoury SJ (2005) Corticotropin-releasing hormone contributes to the peripheral inflammatory response in experimental autoimmune encephalomyelitis. J Immunol. 174(9): 5407-13.

(6) Kontopoulos VK, Chandras C, Karalis K (2006) Terbutaline inhibits corticotropin releasing-hormone (CRH) expression in human trophoblast cells. Journal Matern Fetal Neonatal Med 19(11): 735-9.

(7) Jonas KC, Chandras C, Abayasekara DR, Michael AE (2006) Role for prostaglandins in the regulation of type 1 11beta-hydroxysteroid dehydrogenase in human granulosa-lutein cells. Endocrinology 147(12): 5865-72.

(8) Chandras C, Harris TE, Bernal AL, Abayasekara DR, Michael AE. (2007) PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11beta-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa lutein cells. J Endocrinol. 194(3): 595-602.

(9) Aidinis V, Chandras C, Manoloukos M, Thanassopoulou A, Kranidioti K, Armaka M, Douni E, Kontoyiannis DL, Zouberakis M, Kollias G; Mugen NoE consortium. (2008) MUGEN mouse database; animal models of human immunological diseases. Nucleic Acids Res. 36(Database issue): D1048-54.

(10) Chandras C, Weaver T, Zouberakis M, Hancock JM, Schofield PN, and Aidinis V (2008) Digital Preservation – Financial Sustainability of Biological Data and Material Resources. BioInformatics and BioEngineering, 2008. BIBE 2008, 8th IEEE International Conference on 8-10 Oct. Page(s):1 - 6

(11) Zouberakis M, Chandras C, Hancock JM, Schofield PN, Aidinis V (2008) The Mouse Resource Browser (MRB) – A near-complete registry of mouse resources. BioInformatics and BioEngineering, 2008. BIBE 2008, 8th IEEE International Conference on 8-10 Oct. Page(s):1 - 5

(12) Chandras C, Koutmani Y, Kokkotou E, Pothoulakis C, and Karalis K (2009) Activation of phosphatidylinositol 3-kinase/protein kinase B by corticotropin-releasing factor in human monocytes. Endocrinology 150(10): 4606-4614.

(13) Chandras C, Weaver T, Zouberakis M, Smedley D, Schughart K, Rosenthal N, Hancock JM, Kollias G, Schofield PN, and Aidinis V (2009) Models for financial sustainability of biological databases and resources Database (Oxford). 2009:bap017.

(14) Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J, Wood J; EUMODIC Consortium, de Angelis MH, Brown SD, Hancock JM, Mallon AM. (2010) EuroPhenome: a repository for high-throughput mouse phenotyping data. Nucleic Acids Res. 38(Database issue): D577-85.

(15) Zouberakis M, Chandras C, Swertz M, Smedley D, Gruenberger M, Bard J, Schughart K, Rosenthal N, Hancock JM, Schofield PN, Kollias G, Aidinis V. (2010) Mouse Resource Browsera database of mouse databases. Database (Oxford).2010:baq010.

(16) Smedley D, Schofield P, Chen CK, Aidinis V, Ainali C, Bard J, Balling R, Birney E, Blake A, Bongcam-Rudloff E, Brookes AJ, Cesareni G, Chandras C, Eppig J, Flicek P, Gkoutos G, Greenaway S, Gruenberger M, Hériché JK, Lyall A, Mallon AM, Muddyman D, Reisinger F, Ringwald M, Rosenthal N, Schughart K, Swertz M, Thorisson GA, Zouberakis M, Hancock JM. (2010) Finding and sharing: new approaches to registries of databases and services for the biomedical sciences. Database (Oxford). 2010:baq014.

(17) Chandras C, Zouberakis M, Salimova E, Smedley D, Rosenthal N, Aidinis V. (2012) CreZOOthe European virtual repository of Cre and other targeted conditional driver strains. Database (Oxford). 2012:bas029.

Oral Presentations

(1) Chandras C (2000) Prostaglandin E2 involvement in the steroidogenic response of human granulosa cells to the High Density Lipoproteins. National Ovarian Workshop, UK.

(2) Chandras C, Harris TE, Lopez-Bernal A, Abayasekara DRE & Michael AE (2001) Participation of EP1 and EP2receptor signalling pathways in the steroidogenic response of human granulosa-lutein (hGL) cells to PGE2 Endocrine Abstracts 2: OC30

(3) Chandras C, Zouberakis M, Aidinis V (2007) MMdb: A user’s perspective. CASIMIR 1st Networking meeting, Corfu, Greece.

(4) Chandras C (2008) WP5 – Bioinformatics core – Relational Databases (MDE), MUGEN 4th Annual & Review Meeting, Athens, Greece.

(5) Chandras C (2008) Enhancing mouse phenotypic characterisation based on OBO ontologies. Second Mouse Phenotyping Workshop, June 16-17, 2008, Manchester, UK.(Invited)

(6) Chandras C, Weaver T, Zouberakis M, Hancock JM, Schofield PN, and Aidinis V (2008) Digital Preservation – Financial Sustainability of Biological Data and Material Resources. ΙΕΕΕ International Conference on Bioinformatics and Bioengineering, Athens, Greece.

(7) Chandras C (2009) MKE – RELATIONAL DATABASES MUGEN Mouse Database (MMdb). 5th MUGEN Annual & Review Meeting, January 26-28, Athens, Greece.

(8) Chandras C, Zouberakis M, Schofield PN, Smedley D, Hancock JM, Gkoutos G, Kollias G, Aidinis V (2009) Online Mouse Resources; Phenotypic Characterization in practice. MUGEN Immune Phenotyping Workshop, October 6-8, Athens, Greece.

(9) Chandras C, Smedley D, Hancock JM, Schofield PN, Aidinis V (2010) How could digital preservation of biological data and material resources be financially supported? 3rd Human Variome Project Meeting, May 10-14, Paris, France. (Invited) (10) Chandras C, Kollias G, Aidinis V (2010) Online Mouse Resources; Phenotypic Characterization in practice, Eumodic 3rd Annual Meeting, March 25-26, Brussels, Belgium. (Invited)

(11) Chandras C (2012) TheRAbase; www.therabase.eu BTCure 1stAnnual Scientific Meeting, September 9-11, Prague, Czech Republic.